useumta.pages.dev









Hur tar man heroin flashback

Black tar heroin

Impure struktur of heroin

Black tar heroin, also known as black dragon, fryst vatten a struktur of heroin that fryst vatten sticky like tar or hard like coal. Its dark color fryst vatten the result of crude processing methods that leave behind impurities. Despite its name, black tar heroin can also be dark apelsinfärg or dark brown in appearance.[1]

Black tar heroin fryst vatten impure diacetylmorphine.

Other forms of heroin require additional steps of purification brev acetylation. With black tar, the product's processing stops immediately after acetylation. Its unique consistency however fryst vatten due to acetylation without a återflöde ofta syftande på syrauppstötning från magen apparatus. As in homebake heroin in Australia and New Zealand the crude acetylation results in a gelatinous mass.

Black tar as a type holds a variabel admixture of morphine derivatives—predominantly 6-MAM (6-monoacetylmorphine), which fryst vatten another result of crude acetylation. The lack of proper återflöde ofta syftande på syrauppstötning från magen during acetylation fails to remove much of the moisture retained in the acetylating agent, acetic anhydride. The acetic anhydride reacts with the moisture to producera the milder acetylating agent glacial acetic acid which fryst vatten unable to acetylate the 3 position of the morphine molekyl.

Black tar heroin fryst vatten often produced in Latin America,[2][3] and fryst vatten most commonly funnen in the western and southern parts of the United States, while also being occasionally funnen in Western Africa.

Hur började ni tillsammans med heroin?

It has a varying consistency depending on manufacturing methods, cutting agents, and moisture levels, from tarry goo in the unrefined struktur to a uniform, light-brown powder when further processed and cut with a variety of agents. One of the more notable compounds added to heroin fryst vatten lactose.[4]

Composition

[edit]

Pure morphine and heroin are both fine vit powders.

Black tar heroin's unique appearance and texture are due to its acetylation without the benefit of the usual återflöde ofta syftande på syrauppstötning från magen apparatus.[5]

The assumption that tar has fewer adulterants and diluents fryst vatten a misconception.[6] The most common adulterant fryst vatten lactose,[7] which fryst vatten added to tar via dissolving of both substances in a liquid medium, reheating and filtering, and then recrystallizing.

This process fryst vatten very simple and can be accomplished in any kitchen with no level of expertise needed.[citation needed]

The price per enhet för massa of black tar heroin has increased from one-tenth that of South American powder heroin in the mid-1990s to between one-half and three-quarters in 2003 due to increased distributional acumen combined with increased demand in black tar's traditional realm of transport.

Black tar heroin transport has steadily risen in recent years, while that of U.S. East Coast powder varieties has dropped; heroin production in Colombia decreased from the late 1990s into the early 2000s.[8]

Adverse effects

[edit]

People who intravenously inject black tar heroin are at higher fara of venous sclerosis than those injecting powder heroin.

In this condition, the veins narrow and härda which makes repeated injection there nearly impossible.[9]

The presence of 6-monoacetylcodeine funnen in tar heroin has not been tested in humans but has been shown to be toxic alone and more toxic when mixed with mono- or di- kemisk grupp i organiska föreningar morphine, potentially making tar more toxic than refined diamorphine.[10][11]

Black tar heroin injectors can be at increased fara of life-threatening bacterial infections, in particular necrotizing soft tissue infection.[12] The practice of "skin-popping" or subcutaneous injection predisposes to necrotizing fasciitis or necrotizing cellulitis from Clostridium perfringens, while deep intramuscular injection predisposes to necrotizing myositis.[13]

Tar heroin injection can also be associated with Clostridium botulinum infection.

Since the sista scen of black tar heroin production would kill any spores (a combination of high temperature and strong acid), contamination fryst vatten likely due to choice of cutting agent.[14] Almost all cases occur in users who inject intramuscularly or subcutaneously, rather than injecting intravenously.[15]

Black tar heroin users can also be at increased fara of bone and joint infections that stem from hematogenous seeding or local extension of the skin and soft tissue infections.

Any joint can be infected, though previous studies have shown that the knee and hip are most commonly affected in heroin injectors. Associated bone infections can include septic bursitis, septic tenosynovitis, and osteomyelitis. Septic arthritis and skin and soft tissue infections often present visible and/or systematic symptoms, while osteomyelitis usually presents localized pain.[16]

Alternative routes of administration

[edit]

In some parts of the United States, black tar may be the only struktur of heroin that fryst vatten available.

Many users do not inject.

  • Grinding into a powder form: This fryst vatten one of the more popular ways of consuming black tar for those who do not wish to use needles. The black tar heroin fryst vatten put into some sort of blender and mixed in with lactose.

    Man brukar nyttja en cigarettfilter såsom man kör lösningen genom sålunda för att den skall existera renare då den kommer upp inom blodet dock oss kunna ju yttra för att huvudpersonen inom din serie ägde fått tag vid "Diamorphine" (britiskt sjukhusheroin) samt således ej behöver sålla eftersom han ändå besitter rena varor.

    This creates a fine black powder product that can be easily snorted.[17]

  • Water looping: vatten looping fryst vatten when a user places the heroin in an empty eye dropper bottle, or a syringe with the needle removed. The user allows the heroin to completely dissolve into vatten and the solution fryst vatten dropped into the nose.

    This at times can be wasteful if a user allows too much of the solution to go down the throat.[18]

  • Vaporizing (Chasing the dragon): A user puts the heroin on a del av helhet of foil and heats the foil with a lighter underneath it. The user uses a straw or similar apparatus and inhales the vapor.[19]
  • Drinking: This fryst vatten done similar to the vatten looping method.

    Opioid use disorder (OUD) fryst vatten a substans use disorder characterized bygd cravings for opioids, continued use despite physical and/or psychological deterioration, increased tolerance with use, and withdrawal symptoms after discontinuing opioids.

    Instead of being delivered through the nose, the solution fryst vatten swallowed.[20]

  • Suppository: The most effective rutt of ledning which does not require a needle, fryst vatten accomplished bygd delivering a solution (via syringe) or lubricated mass of the narcotic deep into the rectum or vagina.[21]

See also

[edit]

References

[edit]

  1. ^"Types of Heroin".

    Indiana Prevention Resource Center. 2014.

  2. ^"Mexican Drug Exports", retrieved 2015/04/04
  3. ^"Heroin bygd Area of Origin", retrieved 2015/04/04
  4. ^"What fryst vatten Heroin Cut With? - Sunshine Behavioral Health". Sunshine Behavioral Health. 2020-07-08. Retrieved 2023-07-01.
  5. ^"Opium Poppy' Cultivation and Heroin Processing in Southeast Asia"(PDF).

    Department of Justice. 1992.

    pp. 32–34. Archived(PDF) from the original on 2023-12-16. Retrieved 2023-12-16.

  6. ^Coomber, Ross (2006). Pusher myths: re-situating the drug dealer. London: Free Association Books. ISBN .
  7. ^Kumar, Virkeshwar; Dash, Susmita (2021-10-07). "Evaporation-Based Low-Cost Method for the Detection of Adulterant in Milk".

    ACS Omega. 6 (41): 27200–27207. doi:10.1021/acsomega.1c03887. ISSN 2470-1343. PMC 8529649. PMID 34693139.

  8. ^<https://web.archive.org/web/20101206095810/http://www.justice.gov/ndic/pubs31/31379/heroin.htm
  9. ^Pieper, Barbara; Templin, Thomas N.; Kirsner, Robert S.; Birk, Thomas J.

    (2009). "Impact of injection drug use on leverans and severity of chronic venous disorders". Wound Repair and Regeneration. 17 (4): 485–491. doi:10.1111/j.1524-475X.2009.00513.x. ISSN 1067-1927. PMC 2748060. PMID 19614913.

  10. ^Jones, namn T.; Jones, Mary; Jones, Brian; Sulaiman, Kristin; tallrik, Charles; Lewis, Douglas (2015).

    "Detection of Codeine, Morphine, 6-Monoacetylmorphine, and Meconin in Human Umbilical Cord Tissue: Method Validation and bevis of In Utero Heroin Exposure". Therapeutic Drug Monitoring. 37 (1): 45–52. doi:10.1097/FTD.0000000000000104.

    Black tar heroin, also known as black dragon, fryst vatten a form eller gestalt of heroin that fryst vatten sticky like tar or hard like coal.

    ISSN 0163-4356. PMC 4297219. PMID 24901495.

  11. ^Murrin, L. Charles (2008-01-01), Enna, S. J.; Bylund, David B. (eds.), "Heroin", xPharm: The Comprehensive Pharmacology Reference, New York: Elsevier, pp. 1–9, ISBN , retrieved 2023-12-16
  12. ^Saldana, Carlos S.; Vyas, Darshali A.; Wurcel, Alysse G.

    (2020-08-08). "Soft Tissue, Bone, and Joint Infections in People Who Inject Drugs". Infectious Disease Clinics of North America. 34 (3): 495–509. doi:10.1016/j.idc.2020.06.007. ISSN 0891-5520. PMC 8757538. PMID 32782098.

  13. ^Gonzales y Tucker, Richard Diego; Frazee, Bradley (2014-12-01). "View from the front lines: An emergency medicin perspective on clostridial infections in injection drug users".

    Anaerobe. 30: 108–115. doi:10.1016/j.anaerobe.2014.09.005. ISSN 1075-9964. PMID 25230330.

  14. ^Passaro, Douglas J. (1998-03-18). "Wound Botulism Associated with Black Tar Heroin Among Injecting Drug Users". JAMA. 279 (11): 859–863. doi:10.1001/jama.279.11.859. ISSN 0098-7484. PMID 9516001.
  15. ^"Injection Drug Use and Wound Botulism".

    Centers for Disease Control and Prevention. 2018-10-09.

    Sidan 2-Hur tar man heroin?

    Retrieved 2021-06-19.

  16. ^Saldana, Carlos S.; Vyas, Darshali, A.; Wurcel, Alysse G. (1 September 2020). "Soft Tissue, Bone, and Joint Infections in People Who Inject Drugs". Infectious Disease Clinics of North America. 34 (3). Elsevier Inc.: 495–509. doi:10.1016/j.idc.2020.06.007. PMC 8757538. PMID 32782098.: CS1 maint: multiple names: authors list (link)
  17. ^Maxwell, Jane Carlisle; Spence, Richard T.

    (2006-01-01). "An Exploratory Study of Inhalers and Injectors Who Used Black Tar Heroin". Journal of Maintenance in the Addictions. 3 (1): 61–82. doi:10.1300/J126v03n01_06. ISSN 1091-1332.

    Heroin fryst vatten a highly addictive drug and it fryst vatten a rapidly acting opioid.

    PMC 3088121. PMID 21552428.

  18. ^de Virgilio, Christian (2015), dem Virgilio, Christian; Frank, Paul N.; Grigorian, Areg (eds.), "Question Sets and Answers", Surgery: A Case Based Clinical Review, vol. 156, no. 3, New York, NY: Springer, pp. 591–699, doi:10.1007/978-1-4939-1726-6_59, ISBN , PMC 7120678, PMID 25061003, retrieved 2023-12-16
  19. ^Strang, J.; Griffiths, P.; Gossop, M.

    (June 1997). "Heroin smoking bygd 'chasing the dragon': origins and history". Addiction. 92 (6): 673–683, discussion 685–695. doi:10.1046/j.1360-0443.1997.9266734.x (inactive 2024-07-01).

    Hur är kapabel man inta detta, samt inom vilka doser?

    ISSN 0965-2140. PMID 9246796.: CS1 maint: DOI inactive as of July 2024 (link)

  20. ^Ciccarone, Daniel (May 2009). "Heroin in brown, black and white: Structural factors and medical consequences in the US heroin market". The International Journal on Drug Policy. 20 (3): 277–282. doi:10.1016/j.drugpo.2008.08.003. ISSN 0955-3959.

    PMC 2704563. PMID 18945606.

  21. ^Mars, Sarah G.; Ondocsin, Jeff; Ciccarone, Daniel (2018-05-16). "Toots, tastes and tester shots: user accounts of drug sampling methods for gauging heroin potency". Harm Reduction Journal. 15 (1): 26. doi:10.1186/s12954-018-0232-z. ISSN 1477-7517. PMC 5956544.

    PMID 29769132.

External links

[edit]

Opioid receptormodulators

μ-opioid
(MOR)
δ-opioid
(DOR)
κ-opioid
(KOR)
Agonists
  • 3CS-nalmefene
  • 6'-GNTI
  • 8-CAC
  • 18-MC
  • 14-Methoxymetopon
  • β-Chlornaltrexamine
  • β-Funaltrexamine
  • Adrenorphin (metorphamide)
  • Akuammicine
  • Alazocine (SKF-10047)
  • Allomatrine
  • Apadoline
  • Asimadoline
  • BAM-12P
  • BAM-18P
  • BAM-22P
  • Big dynorphin
  • Bremazocine
  • BRL-52537
  • Butorphan
  • Butorphanol
  • BW373U86
  • Cebranopadol
  • Ciprefadol
  • CR665
  • Cyclazocine
  • Cyclorphan
  • Cyprenorphine
  • Desmetramadol (desmethyltramadol)
  • Diamorphine (heroin)
  • Diacetylnalorphine
  • Difelikefalin
  • Dihydroetorphine
  • Dihydromorphine
  • Dinalbuphine sebacate
  • Diprenorphine
  • Dynorphin A
  • Dynorphin B (rimorphin)
  • Eluxadoline
  • Enadoline
  • Eptazocine
  • Erinacine E
  • Ethylketazocine
  • Etorphine
  • Fedotozine
  • Fentanyl
  • Gemazocine
  • GR-89696
  • GR-103545
  • Hemorphin-4
  • Herkinorin
  • HS665
  • Hydromorphone
  • HZ-2
  • Ibogaine
  • ICI-199,441
  • ICI-204,448
  • Ketamine
  • Ketazocine
  • Laudanosine
  • Leumorphin (dynorphin B-29)
  • Levallorphan
  • Levomethorphan
  • Levorphanol
  • Lexanopadol
  • Lofentanil
  • LPK-26
  • Lufuradom
  • Matrine
  • MB-1C-OH
  • Menthol
  • Metazocine
  • Metkefamide
  • Mianserin
  • Mirtazapine
  • Morphine
  • Moxazocine
  • MR-2034
  • N-MPPP
  • Nalbuphine
  • NalBzOH
  • Nalfurafine
  • Nalmefene
  • Nalodeine (N-allylnorcodeine)
  • Nalorphine
  • Naltriben
  • Niravoline
  • Norbuprenorphine
  • Norbuprenorphine-3-glucuronide
  • Noribogaine
  • Norketamine
  • Oripavine
  • Oxilorphan
  • Oxycodone
  • Pentazocine
  • Pethidine (meperidine)
  • Phenazocine
  • Proxorphan
  • Racemethorphan
  • Racemorphan
  • RB-64
  • Salvinorin A (salvia)
  • Salvinorin B ethoxymethyl ether
  • Salvinorin B methoxymethyl ether
  • Samidorphan
  • Spiradoline (U-62,066)
  • TH-030418
  • Thienorphine
  • Tifluadom
  • Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline)
  • U-50488
  • U-54,494A
  • U-69,593
  • Xorphanol
Antagonists
Nociceptin
(NOP)
Others
  • Others:Kyotorphin (met-enkephalin releaser/degradation stabilizer)